PRODUCTS
IBSA specialises in the research and development, production and marketing of hyaluronic acid-based products
Sinovial Product Benefits
![Raggruppa 707@2x Raggruppa 707@2x](https://cdn.sinovial.co.uk/wp-content/uploads/2021/07/Raggruppa-707@2x.png)
Long term effectiveness with greater resistance to breakdown of hyaluronidase.
![Raggruppa 337@2x Raggruppa 337@2x](https://cdn.sinovial.co.uk/wp-content/uploads/2021/07/Raggruppa-337@2x.png)
Very high concentrations of hyaluronic acid, with low viscosity and ease of injection
![Raggruppa 296@2x Raggruppa 296@2x](https://cdn.sinovial.co.uk/wp-content/uploads/2021/07/Raggruppa-296@2x.png)
Produced sustainably and ethically with no animal derivatives or chemical processing
Concentration % GAGs across available UK visco-supplementation products
![GAG barchart GAG barchart](https://cdn.sinovial.co.uk/wp-content/uploads/2024/04/GAG-barchart.jpg)
Glycosaminoglycans (GAGs) form a key role in the rheology of endogenous synovial fluid. Synovial fluid provides nourishment to hyalin cartilage, lubrication of joint surfaces and a viscoelastic environment to dissipate load bearing and sheer forces. In degenerative joint conditions, there is a reduction in synovial fluid and GAGs thus reducing these three key functions.
Providing visco-supplementation to a degenerative joint with a high GAG concentration in a hybrid cooperative complex preparation aims to restore the rheological properties of endogenous synovial fluid functions.
Domżalski, M., Migliore, A. A Review of the Clinical Effectiveness and Safety of Hybrid Cooperative Complexes in Intra-articular Viscosupplementation. Rheumatol Ther 9, 957–974 (2022). https://doi.org/10.1007/s40744-022-00450-z
![Sinogel 3ml Sinogel 3ml](https://cdn.sinovial.co.uk/wp-content/uploads/2024/01/Sinogel-3ml.jpg)
Hybrid Cooperative complexes of high MW HA combined with sodium chondroitin held by hydrogen bonds